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PureStem™ Osteogenic Package SK11, NCr-fac & Meso-prx Progenitor

CAT #: LM-OST-SK11

The PureStem Osteogenic Package SK11 includes the human clonal progenitor line PureStem SK11, NCr-fac & Meso-prx Progenitor, specific growth media and a osteogenic differentiation kit. When following the recommended protocols, the differentiated cells express late markers specific to mature osteocytes (SPP1, BGLP,IBSP,ALPL) and their related extracellular matrix, including type 1 collagens (COL1A1).

This package provides the basis for study of osteogenesis and endochondral/membranous bone development and related diseases, such as Osteochondral defects and possible repair of  long bone fractions.

Contents of package

Differentially expressed positive mRNA markers (by microarray):

SPP1, BGLP, IBSP, ALPL, COL1A1

Experimental Data

  • This package was successfully applied to achieve in vitro differentiation of SK11 to functional osteocytes

Growth Media:

Growth conditions provided in product data sheet. Growth media included in package. LifeMap recommends using Progenitor growth media EM-1005, which is optimized for growth of PureStem SK11, NCr-fac & Meso-prx Progenitor.

Differentiation Protocols:

Differentiation protocols are detailed in the product datasheet.

Availability:

3 weeks

References

1 West MD, Sargent RG, Long J, Brown C, Chu JS, Kessler S, Derugin N, Sampathkumar J, Burrows C, Vaziri H, Williams R, Chapman KB, Larocca D, Loring JF, Murai J. 2008 The ACTCellerate initiative: large-scale combinatorial cloning of novel human embryonic stem cell derivatives. Regen Med. 3(3):287-308

Restrictions

This package and its components are provided for research purposes only. They are not for human use, and may not be used for commercial purposes. The user is responsible for proper handling upon receipt.
$1,040.00 $1,090.00  
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Product Highlights

  • High propagation capacity
  • Clonally pure population
  • Demonstrated in vitro osteogenic differentiation
  • High ostegenic efficiency compared to MSCs

Applications:

  • Studying osteogenesis
  • Studying bone-related diseases
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About HyStem Hydrogel

The HyStem Hydrogel is a xeno-free Hyaluronan-based hydrogel product designed for optimal culturing of cells. HyStem can be customized by adding extracellular matrix (ECM) proteins or cell attachment peptides into the hydrogel to provide attachment site and/or differentiation signals. HyStem Hydrogels can also be varied by changing the hydrogel rigidity to match that of the native cell environment.

HyStem Hydrogel is recommended for optimal differentiation for this product.

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Contents of package

  • purestem sk11 ncr fac meso prx progenitor
  • osteogenic differentiation kit em 2003
  • progenitor growth media em 1005
Total: $1,040.00
$1,090.00
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